Category Archives: Science

Researchers show that introduced tardigrade proteins can slow metabolism in human cells | ScienceDaily

Tardigrade proteins are potential candidates in technologies centered on slowing the aging process and in long-term storage of human cells.

Source: Researchers show that introduced tardigrade proteins can slow metabolism in human cells | ScienceDaily

Is there anything tardigrades can’t do? 🙂

University of Wyoming researchers have gained further insight into how tardigrades survive extreme conditions and shown that proteins from the microscopic creatures expressed in human cells can slow down molecular processes.

This makes the tardigrade proteins potential candidates in technologies centered on slowing the aging process and in long-term storage of human cells.

‘Water bear’ genomes reveal the secrets of extreme survival

‘Water bear’ genomes reveal the secrets of extreme survivalby Casey McGrath, Society for Molecular Biology and EvolutionA photograph of the tardigrade Ramazzottius varieornatus, in the center of a phylogeny of CAHS, the largest of the six desiccation-related protein families analyzed in this study. Credit: Kazuharu Arakawa, Keio Institute of Advanced BiosciencesTardigrades may be nature’s ultimate survivors. While these tiny, nearly translucent animals are easily overlooked, they represent a diverse group that has successfully colonized freshwater, marine, and terrestrial environments on every continent, including Antarctica.

Source: ‘Water bear’ genomes reveal the secrets of extreme survival

Monday Musings — 22JAN24

From a commencement speech at Harvard by Charlie Munger (How to Guarantee a Life of Misery):

My third prescription for misery is to go down and stay down when you get your first, second, third severe reverse in the battle of life. Because there is so much adversity out there, even for the lucky and wise, this will guarantee that, in due course, you will be permanently mired in misery. Ignore at all cost the lesson contained in the accurate epitaph written for himself by Epictetus: “Here lies Epictetus, a slave, maimed in body, the ultimate in poverty, and favoured by Gods.”

The rest is pretty good too.

https://www.space.com/barbenheimer-star-defies-explanation

a purple and blue explosion behind the periodic table of elements The newly discovered Barbenheimer Star exploded in a supernova billions of years ago, leaving behind a cloud of unusual elements in its wake. (Image credit: University of Chicago/SDSS-V/Melissa Weiss)

Scientists have discovered evidence of a massive star from the early universe that does not fit with our current understanding of the cosmos. 

Epic: The Musical is a loose adaptation of Homer’s “The Odyssey” by Jorge Rivera-Herrans, who wrote the music and lyrics and also orchestrated and produced the tracks. His song clips and process videos have gone viral on social media with over 60 million views across TikTok, Instagram, and YouTube. The yet-to-be-released musical also has an active Discord fan community of over 30,000 people who share fanart, memes, fan theories, cover songs, positive affirmations, and tattoos of the lyrics.

Free to listen on Spotify, or get the ones that have been released on Bandcamp:

https://jayherrans.bandcamp.com/album/epic-the-troy-saga-original-concept-album

A link filled Monday, of stuff that interested me this week. Not much musing going on is there. Just wanted to share good stuff. We all need that don’t we. See you next week.

Floating sea farms: A solution to feed the world and ensure freshwater by 2050

The sun and the sea—both abundant and free—are being harnessed in a unique project to create vertical sea farms floating on the ocean that can produce fresh water for drinking and agriculture.

 

Freshwater accounts for just 2.5% of the world’s water and most of this is not accessible because it’s trapped in glaciers, ice caps or is deep underground,” Dr. Owens says. “It’s not that freshwater is dwindling either, but the small amount that exists is in ever increasing demand due to population growth and climate change.

“The fact that 97.5% of the world’s water is in our oceans—and freely available—it is an obvious solution to harness the sea and sun to address growing global shortages of water, food, and agricultural land. Adopting this technology could improve the health and welfare of billions of people globally.”

Source: Floating sea farms: A solution to feed the world and ensure freshwater by 2050

MIT engineers create an energy-storing supercapacitor from ancient materials | MIT News | Massachusetts Institute of Technology

MIT engineers created a carbon-cement supercapacitor that can store large amounts of energy. Made of just cement, water, and carbon black, the device could form the basis for inexpensive systems that store intermittently renewable energy, such as solar or wind energy.

Source: MIT engineers create an energy-storing supercapacitor from ancient materials | MIT News | Massachusetts Institute of Technology

Using mycelium to create a self-healing wearable leather-like material

Source: Using mycelium to create a self-healing wearable leather-like material

 

A pair of biotechnologists at Newcastle University, working with a colleague from Northumbria University, all in the U.K., have developed a way to use mycelium to create a self-healing wearable material. In their paper published in the journal Advanced Functional Materials, Elise Elsacker, Martyn Dade-Robertson and Meng Zhang, describe their process and how well it worked when tested.

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Mycelium is a thread-like structure produced by some types of fungus. Prior research has shown that fungal colonies can arise with intertwining branching mycelium, resulting in the growth of large, matted structures. Such structures are typically found in the ground. Prior research has also shown that mycelium mats can be treated to produce a material known as mycelium leather, due to its resemblance to cow hide leather.

But as the research trio note, such treatments tend to kill chlamydospores—little nodules that allow the material to spring back to life given the right circumstances. After examining samples and the leathering process, they considered the possibility of changing things a bit to prevent killing the chlamydospores, which could allow the material to self-heal when put into a conducive environment.

The researchers grew their own batch of mycelium by adding active chlamydospores to a watery batch of carbohydrates, proteins and other nutrients. They then allowed enough time to pass for a thick skin to form on the liquid. The team then pulled the skin off the liquid and laid it out to dry. As it dried, they applied a mix of temperatures and chemicals that allowed the material to become leather-like without killing the embedded chlamydospores.

Testing of the resulting material showed it to be similar to other mycelium leathers in looks and characteristics. To find out if it could heal itself, the group punched holes in it and then placed it in a vat filled with the same liquid bath that had been used in its creation. Then they laid it out to dry, and as it did so, they noted that over time, the revived chlamydospores filled in the holes. Testing showed that the newly restored material was just as strong as an undamaged control sample, though they noted that it was still possible to see where the holes had been

Sarcopenia, Weight loss, and Protein

Of interest to me, and anyone on chemo, because the meds tend to cause weight loss, and muscle loss.

Source: The Arrow #112 – by Michael Eades – The Arrow

A roasted chicken thigh will give you about 30 gm of protein, of which close to 3 gm will be leucine. That’s enough to kick off mTOR and keep it working for 4-6 hours. Don’t think you can cheat the system by taking in smaller amounts of protein all day long or even larger amounts. You want mTOR to be pulsatile, not continuous. So, big doses. If you don’t feel like a chicken thigh for breakfast — and you may not — you can add whey in a shake. It’s a good source of leucine.